Using procedures recommended by specific standards (ABNT – NBR 9804 – Hospital Autoclave and in the Brazilian Pharmacopeia (4th edition) – Sterility test), IPT evaluates equipment with different types of physical or chemical antimicrobial action. Physical processes evaluated include dry heat, humid heat, ultraviolet radiation and ozonization. The most important Read more…
Fire-fighting equipment and systems, domestic refrigerators and refrigeration installations and air conditioning systems use gases that may contain substances that are harmful to the ozone layer, such as Carbon, Fluoride and Chlorine (CFCs), Carbon, Fluoride and Bromide (Halon), carbon tetrachloride and trichloroethanes. A complete list of substances is available in Read more…
IPT’s approach to biotechnology stands out for its ability to act in all the stages of development of a bioprocess, from the screening of different microorganisms or construction of recombining strains to the design of an industrial reactor to obtain bioproducts. The integration of microbiology and recombinant DNA technology with Read more…
Vaccines and biopharmaceutical products are typically proteins, viruses or viral particles which require complex production systems, in most cases involving application of recombinant DNA technology. Some of these bioproducts, which are less complex in terms of post-transcription transformation (glycolyation, phosphorylation, disulphate bridges, and amidation, etc.) can be produced in yeasts Read more…
Growing concern about the environment has increased commercial interest in recycling and reusing materials. Therefore, the use of residues to generate products of higher added value is of interest, since it combines a solution for their treatment with valorization of these residues. IPT is currently developing bioprocesses aimed at adding Read more…
Bioreactor operation is based on the process kinetics and the fluid dynamics of the system. To control the process kinetics, methodologies are required to measure the concentration of the variables of state, such as biomass produced, substrate consumption, and products formed during the process. For this control, IPT is equipped Read more…
Increase of scale means to reproduce in larger size equipment the results obtained successfully on a smaller scale. The development of processes in bioreactors is generally carried out on three scales: bench scale, in which basic procedures and process parameters are developed; pilot scale, in which the operating conditions are Read more…
IPT is specialized in the culture of microorganisms of scientific, industrial and environmental interest. Microorganisms are preserved in lyophilized form, by ultra-freezing at -80°C and other alternative methods for specific strains. The Institute has a collection containing a variety of microorganisms for control, monitoring and validation (sterilization tests, autoclave validation, Read more…
Bioproducts created from enzymes or selected or recombined microorganisms can be cultured in rotating incubators (shakers) or in bioreactors of different volumes and capacities. These incubators enable experiments to be performed at controlled temperatures and shaking frequency. Bioreactors, in addition to the above, allow for the control of pH, level, Read more…
Microencapsulation involves a group of specific techniques that allow for the preparation of functional particles, and consists of a support material (encapsulating agent) and an active compound distributed in its core. Microencapsulation technology requires extremely strict control of specific properties of the product, whose action is programmed or controlled. IPT Read more…
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