Abstract: Chikungunya fever (CHIKF), caused by the Chikungunya virus (CHIKV), manifests as acute febrile illness often associated with polyarthritis and polyarthralgia. Although the acute symptoms resolve within two weeks, many patients experience prolonged joint pain and inflammation, resembling rheumatoid arthritis (RA). This study aimed to identify molecular markers related to Leia mais…
Referência: ANDREOTTI, Isabela Aparecida de Araujo; GRIEP, Gabriel; PATIÑO-NARIÑO, Edgar A.; OLIVEIRA, Aline Furtado; BEJARANO, Martha Lucia Mora; GONGORA-RUBIO, Mario Ricardo; WISINEWSKI, Henrique Reis; MIRANDA, Beatriz N.M.; SILVA, Leonardo R.B.; VERONA, Bruno M.; BALBINO, Tiago A.; BONAMINO, Martín H. Enhancing microfluidic device design for CART-T cell transfection: integrating soft lithography Leia mais…
Abstract: To synthesize HER2 aptamer-conjugated iron oxide nanoparticles with a coating of poly(2-(dimethylamino) ethyl methacrylate)–poly(2-methacryloyloxyethylphosphorylcholine) block copolymer (IONPPPs). Characterization covered molecular structure, chemical composition, thermal stability, magnetic characteristics, aptamer interaction, crystalline nature and microscopic features. Subsequent investigations focused on IONPPPs for in vitro cancer cell identification. Results demonstrated high biocompatibility Leia mais…
Abstract: DNA data storage based on synthetic oligonucleotides is a major attraction due to the possibility of storage over long periods. Nowadays, the quantity of data generated has been growing exponentially, and the storage capacity needs to keep pace with the growth caused by new technologies and globalization. Since DNA Leia mais…
Referência: MARTINS, André Guilherme da Costa; AOYAGI, Thiago Yuji; SOUZA, Diego T. de; LEAL, Adriano Galindo; MIRANDA, Matheus M. de; SILVA, Cristina Maria Ferreira da; UEDA, Eduardo Takeo; FEITOSA, Allan E.; PARADA, Marcelo; FUJITA, André; VERONA, Bruno Marinaro. Pantheon DNA data storage CODEC. In: CONGRESSO BRASILEIRO DE BIOINFORMÁTICA, 20., 2024, Leia mais…
Referência: MARTINS, Andre Guilherme da Costa. Challenges of encoding digital data into DNA sequences and decoding it back to digital. São Paulo, 2024. (Palestra apresentada na disciplina de Biologia Molecular do Programa de Pós-graduação Multicêntrico em Bioquímica e Biologia Molecular, do Campus Centro-Oeste Dona Lindu-UFSJ) Acesso aos slides da apresentação Leia mais…
Abstract: Metformin (MET), an antidiabetic compound, has received increasing attention, as it cannot be effectively removed during conventional wastewater treatment processes and may act as an endocrine disruptor. Electron beam irradiation (EBI) is an eco-friendly process able to degrade and neutralize biohazardous pollution almost instantly. In this context, this study Leia mais…
Abstract: To synthesize HER2 aptamer-conjugated iron oxide nanoparticles with a coating of poly(2-(dimethylamino) ethyl methacrylate)–poly(2-methacryloyloxyethylphosphorylcholine) block copolymer (IONPPPs). Characterization covered molecular structure, chemical composition, thermal stability, magnetic characteristics, aptamer interaction, crystalline nature and microscopic features. Subsequent investigations focused on IONPPPs for in vitro cancer cell identification. Results demonstrated high biocompatibility Leia mais…
Referência: VERONA, Bruno Marinaro. DNA Data Storage: motivações, oportunidades de desafios. São Paulo, 2024. 26 slides. (Palestra apresentada na disciplina de Biologia Molecular do Programa de Pós-graduação Multicêntrico em Bioquímica Molecular, do Campus Centro-Oeste Dona Lindu-UFSJ) Acesso aos slides da apresentação da Palestra em PDF: https://escriba.ipt.br/pdf/179054
Abstract: DNA is an intelligent data storage medium due to its stability and high density. It has been used by nature for over 3.5 billion years. Compared with traditional methods, DNA offers better compression and physical density. DNA can retain information for thousands of years. However, challenges exist in scalability, Leia mais…
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