Immobilization of a fungal fructosyltransferase onto sílica gel and glutaraldehydr-functionalized sílica gel for biocatalytic application

Abstract: The immobilization of fructosyltransferase enzymes has been identified as an essential strategy for the production of fructooligosaccharides (FOS) in heterogeneous reaction systems. This study investigated the applicability of silica gel and silica gel functionalized with glutaraldehyde as porous inorganic supports for the immobilization of the extracellular fructosyltransferase from Aspergillus Leia mais…

Use of demerara and VHP sugars combinedwith various notrogen sources for enhanced fructosyltranferase production in Aspergillus oryzae IPT-301

Abstract: This study investigated the effect of low-cost carbon and nitrogen sources on fructosyltransferase (FTase) production by Aspergillus oryzae IPT-301, aiming to optimize the enzymatic synthesis of fructooligosaccharides (FOS), prebiotic compounds valued for their bifidogenic effects. FTase is a key enzyme in transfructosylation, the central step in FOS production. To Leia mais…

Abrigos transitórios como instrumentos de política pública municipal de inclusão habitacional

Referência: RESENDE, Maurício Marques. Abrigos transitórios como instrumentos de política pública municipal de inclusão habitacional. Municípios de São Paulo, A Revista da Associação Paulista de Municípios, v.12, n.111, p. 12-13, fev.-mar., 2026. Acesso ao artigo no site do Periódico: https://apaulista.org.br/wp-content/uploads/2026/02/MUSP_Ed111_digital.pdf

Balancing torque, efficiency, and emissions: a framework for engine optimization using modern metaheuristics

Abstract: Modern internal combustion engines must satisfy increasingly strict and often conflicting requirements: high torque demand must be delivered without sacrificing fuel efficiency, while emissions compliance depends on maintaining suitable exhaust thermal conditions for effective aftertreatment operation. These objectives are strongly coupled and highly nonlinear, so improving one metric can Leia mais…

Geological and geotechnical in urban áreas: an application to the São Paulo metropolitan área

Abstract: The demand for underground construction to support urban development is growing in major metropolitan centers worldwide. As Brazil’s economic hub, São Paulo faces significant infrastructure challenges, prompting the need for expanded underground networks. Understanding the geotechnical characteristics of subsurface materials is therefore essential. In this context, three-dimensional geological modeling Leia mais…

A dried spot liquid chromatography method to measure 3,4-methylenedioxymethamphetamine and 3,4-methylenedioxymphetamine in oral fluid

Abstract: MDMA and MDA are among the stimulant drugs most frequently encountered in forensic casework, and oral fluid represents a practical biological matrix for their detection. However, liquid oral fluid requires refrigeration, is susceptible to degradation, and can be logistically demanding for routine laboratories. Dried Oral Fluid Spots (DOFS) offer Leia mais…

Caracterização química e mineralógica de argamassa histórica do Convento Franciscano de Ipojuca do século XVII: contribuições para reconstituição de traço = Chemical and mineralogical characterization of historic mortar from the 17th century Franciscan Convent of Ipojuca: contributions toward the reconstruction of the binder:aggregate ratio

Resumo: Um edifício histórico integra diferentes tipos de alvenaria, texturas e características. Tais características possuem dependência de vários fatores. Por guardar valores culturais, históricos e científicos, os restauros de argamassas históricas não podem ser realizados sem uma minuciosa análise. Portanto, se faz necessário uma caracterização detalhada levando em conta a Leia mais…

Preliminary studies on the distribution of stable Pb and Pb-210 in the maternal and fetal portions of human placentas

Abstract: Fetal growth and survival are solely dependent on the placenta, making thecharacterization of toxic elements in this tissue crucial for understanding exposure duringpregnancy. Stable lead (Pb) and Pb-210 are toxic elements of particular interest in thiscontext. Stable Pb has been linked to developmental changes in children, while Pb-210, abeta-emitting Leia mais…

Avaliação comparativa de arquiteturas RAG para mitigação de alucinações em LLMs

Resumo: Esta pesquisa avaliou comparativamente o desempenho de três arquiteturas de Recuperação Aumentada por Geração (RAG) — RAG Tradicional, Tree-RAG e MultiQuery RAG — com o framework LangChain, para identificar a abordagem mais eficaz na redução de alucinações e no aumento da precisão de Modelos de Linguagem Grandes (LLMs) em Leia mais…

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