Xenotransplante no Brasil: perspectivas, avanços e desafios para o futuro da medicina

Referência: GOMES, Helena Corrêa de Araújo. Xenotransplante no Brasil: perspectivas, avanços e desafios para o futuro da medicina. São Paulo, 2024. 12 slides. (Palestra apresentada na ILP, telepresencial) Acesso a apresentação da Palestra no site do Evento: https://www.al.sp.gov.br/noticia/?27/11/2024/transplante-de-orgaos-de-animais-em-humanos-e-tema-de-palestra-promovida-pelo-ilp

O Núcleo de Tecnologias Avançadas para o bem-estar e saúde aplicados às ciências da vida do IPT e sua contribuição para os municípios

Resumo: O ano de 2024 é um ano de celebrações no Instituto de Pesquisas Tecnológicas (IPT), o instituto completa 125 anos da sua fundação. Uma trajetória marcada pela excelência, desempenhando um papel essencial nos avanços científicos e tecnológicos em diferentes setores, bem como para solucionar os desafios da sociedade do Leia mais…

Fast methodology for photoinduction and detection of mycosporine and mycosporine-like amino acids (MAAs) in yeasts

Referência: BARBOSA, Renan Santini; SILVA, Gabriel Martins; SANTOS, Ronaldo Silva; PADILLA, Adrian Adolfo Alvarez; OLIVEIRA, Sandra Souza de; YAMAGUCHI, Lydia Fumiko; MEDEIROS, Lívia Soman de; VALLIM, Marcelo Afonso; PACON, Renata Castiglioni. Fast methodology for photoinduction and detection of mycosporine and mycosporine-like amino acids (MAAs) in yeasts. In: INTERNATIONAL SYMPOSIUM ON Leia mais…

Chemical constituents of Coccoloba peltata Schott leaves and Their cytotoxic activities

Abstract: Chromatographic fractionation of CH2Cl2:MeOH (1:1) extract of Coccoloba peltata Schott cultivated in Egypt afforded four compounds, lupeol acetate (1), ent-13-epi-manoyl oxide (2), 5-methoxymethyl7,8-dimethyltocol (3), and α-tocopherol quinone (4). The planar structures of the isolated compounds were concluded based on HRESIMS and NMR spectroscopy. X-ray crystallography of 2 is reported Leia mais…

Biodegradation of polycyclic aromatic hydrocarbons (PAHs) by Diutina mesorugosa isolated in the Amazon, Brazil

Abstract: There is a demand for new microorganisms with the potential to degrade recalcitrant petroleum compounds, such as polycyclic aromatic hydrocarbons (PAHs). The objective of this research was to evaluate the potential of the AM15 strain isolated from water samples from the effluent dike of the Urucu petroleum Province, to Leia mais…

Anthracosis particulate matter causes changes in macrophages inflammatory response and in expression of genes related to xenobiotics metabolismo in co-culture of macrophages with BEAS-2B airway cells

Referência: FRIAS, Daniela Perroni; VIEIRA, Gabirela Lima; SMELAN, Juliana; LACERDA, João Paulo Amorin de; MAUAD, Thais; DOLHNIKOFF, Marisa; MACCHIONE, Mariangela. Anthracosis particulate matter causes changes in macrophages inflammatory response and in expression of genes related to xenobiotics metabolismo in co-culture of macrophages with BEAS-2B airway cells. In: ERS INTERNATIONAL CONGRESS, Leia mais…

Beyond the MEP pathway: a novel kinase required for prenol utilization by malária parasites

Abstract: A proposed treatment for malaria is a combination of fosmidomycin and clindamycin. Both compounds inhibit the methylerythritol 4-phosphate (MEP) pathway, the parasitic source of farnesyl and geranylgeranyl pyrophosphate (FPP and GGPP, respectively). Both FPP and GGPP are crucial for the biosynthesis of several essential metabolites such as ubiquinone and Leia mais…

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