Artigos Técnicos
rBCG-LTAK63 enchances protection aginst tuberculosis by inducing autophagy and circadian gene regulation
Abstract: Tuberculosis (TB) remains a global public health challenge, with the current BCG vaccine providing limited efficacy in adults, and available treatments being lengthy and debilitating. To overcome these challenges, we have previously developed a recombinant BCG strain expressing the detoxified E. coli Heat-Labile Toxin (LTAK63), providing increased protection in Leia mais…