Beyond the first case of Chagas diasease: the Berenice strain as a model for understanding long-term Trypanosoma cruzi infection

Abstract: Here, we review the key findings on the genetic characterisation of Berenice strains of Trypanosoma cruzi isolated from a 2-year-old child, Berenice, the first patient with Chagas disease described in the literature in 1909. Be-62 and Be-78 strains were isolated from Berenice when she was 55 and 71 years Leia mais…

Método numérico para a estimativa de ruído hidrodinâmico aplicado a umpropulsor de submarino = Numerical method for the assessment of hydrodynamic noise applieda to a submarine propeller

Resumo: A discrição acústica é crucial para a sobrevivência e eficácia operacional de submarinos. Entre os diversos tipos de ruído emitidos, o ruído hidrodinâmico relaciona-se diretamente à operação do propulsor, à forma do casco e aos seus apêndices. Este estudo propõe um método numérico para avaliar a emissão de ruído Leia mais…

Gold nanoparticle-DNA conjugates: an enzymatic DNA synthesis platform

Abstract: Leveraging the well-established properties of gold nanoparticle (AuNP)-DNA conjugates, this research explored a novel methodology for controlled enzymatic DNA synthesis using gold nanoparticle (AuNP)-DNA conjugates as a solid platform. To this end, Hybrid Nanoparticles (HNPs) were meticulously engineered through the functionalization of AuNPs with rationally designed DNA initiator molecules. Leia mais…

Evaluation of permanent embeddable reference electrodes in solution and concrete specimen

Abstract: Monitoring concrete structures is crucial for assessing the corrosion risk of steel reinforcement and optimizing maintenance strategies. This study evaluated the MnO₂/NaOH, Ag/AgCl, and Ti/MMO permanent, embeddable reference electrodes, which are rarely known or used in Brazil for corrosion monitoring. The electrodes underwent assessment tests, immersion tests in solutions Leia mais…

Optimizing the design of subsea rigid pipelines in utra-deep Waters of the Brazilian pre-salt, thrpugh full-scale axial pipe-soil interaction tests

Abstract: This paper introduces a novel methodology for addressing the complex behavior of axial pipe-soil interaction in soft marine clays, considering drained, undrained and partially drained soil responses. The results of the proposed methodology are compared with those obtained using the traditional alpha approach for determining the axial friction factor. Leia mais…

A literature review about the development of accelerometers as non-seismic soil landsilide tilting sensors

Abstract: Monitoring is an element of landslide early warning systems. Fukuzono’s method, based on displacement and velocity monitoring, is one of the most popular methods for slope time of failure (TOF) prediction. This critical literature review aimed to systematically analyze the state-of-the-art accelerometers used for slope monitoring and TOF prediction. Leia mais…

Monitoring water percolation in a laboratory compacted soil dam using time-lapse electrical resistivity tomography

Abstract: Compacted soil dams are critical structures for mining, water supply and power generation, particularly in tropical regions. Monitoring these dams is essential throughout their lifetime, as variations in reservoir water levels due to drought, rainfall or operational changes can significantly affect soil saturation and stability. This study developed a Leia mais…

Application of na agro-waste for the immobilization of microbial fructosyltransfarase: a new alternative for fructooligosaccharide production

Abstract: This work evaluated the use of corncob as a support for the immobilization of an extracellular fructosyltransferase (E.C. 2.4.1.9) from Aspergillus oryzae IPT-301, aiming at the synthesis of a stable biocatalyst for the production of fructooligosaccharides. The transfructosylation activity of the immobilized enzyme was maximized via experimental design. Additionally, Leia mais…

Fructooligosaccharides: a comprehensive review on their microbial source, functioal benefits, production technology, and market prospects

Abstract: Fructooligosaccharides (FOSs) are carbohydrates of high nutritional value with various prebiotic properties. Optimizing their production process is of significant interest for expanding commercial-scale production. This review discusses the properties and potential applications of FOSs, addressing production challenges and providing an economic market analysis. Bibliometric analysis of data concerning the Leia mais…

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