Estudo da adsorção do ácido acetilsalicílico em peneiras moleculares

Abstract:

Molecular sieves can be used as matrix host to encapsulate several drugs. Here we studied the adsorption of acetylsalicylic acid (ASA) in HUS-Y, HZSM-5 and silicalite-1 zeolites, and in the mesoporous sieve Si-MCM-41, in order to compare their adsorption capacities. The materials used presented generally good performance for ASA adsorption. Among the zeolites, HZSM-5 adsorbed relatively more drug than the others. The Si-MCM41 samples synthesized with fumed silica presented better performance for adsorption than those ones synthesized with TEOS. The materials were characterized by XRD, SEM and TEM, N2 physisorption and infrared spectroscopy.


Reference:
ASSUMPÇÃO, G.A.; FELISBINO, Romilda F.; CARDOSO, Dilson; POÇO, João Guilherme Rocha; GOMES, Eliezer L. Estudo da adsorção do ácido acetilsalicílico em peneiras moleculares. In: ENCONTRO BRASILEIRO SOBRE ADSORÇÃO, 10., 2014, Guarujá. Anais…8 p.

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